Fig. 9
From: Therapeutic efficacy of nanoparticles and routes of administration
Transport mechanism through blood brain barrier. Transport routes across the blood–brain barrier. Pathways (a-f) are commonly for solute molecules; and the route (g) involves monocytes, macrophages and other immune cells and can be used for any drugs or drugs incorporated liposomes or nanoparticles. [Adapted from reference with permission; N.J. Abbott, L. Ronnback, E. Hansson, Astrocyte-endothelial interactions at the blood–brain barrier, Nat Rev. Neurosci 7 (2006) 41–53] [192]