Fig. 2
From: Therapeutic efficacy of nanoparticles and routes of administration
Chitosan based drug delivery. Chitosan containing 5-ASA capsules were coated with hydroxypropyl methylcellulose phthalate as an enteric coating material. After the oral administration of chitosan 5-ASA capsules, disintegration of capsules was assumed by microbial enzyme degradation along with the low acidic pH in the colon. Moreover, chitosan facilitate to stay 5-ASA in the large intestinal mucosa over a period of time and accelerates the healing of TNBS-induced colitis