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Table 3 OFM-Ag Antimicrobial Effectiveness Spectrum and Wear Time Data

From: Ionic silver functionalized ovine forestomach matrix – a non-cytotoxic antimicrobial biomaterial for tissue regeneration applications

Microbial Type Species Log Reduction Value
1 Day 3 Days 7 Days
Gram positive Methicillin Resistant Staphylococcus aureus (MRSA) 7.0 > 8.5 7.8
Staphylococcus epidermidis (coagulase negative) 8.3 > 8.6 > 8.6
Streptococcus pyogenes (Group A, β-hemolytic) > 7.6 > 7.6 > 7.6
Vancomycin Resistant Enterococcus faecalis (VRE) 7.5 7.8 > 8.2
Gram negative Acinetobacter baumannii > 8.6 > 8.6 > 8.6
Escherichia coli > 6.9 > 6.9 > 6.9
Pseudomonas aeruginosa > 9.6 > 9.6 > 9.6
Fungi Candida albicans 6.1 > 8.9 > 8.9
Candida parapsilosis 7.3 > 7.6 > 7.6
Candida glabrata 6.6 > 8.5 > 8.5
Aspergillus brasiliensis (niger) 1.8 > 5.3 > 5.3
  1. Values represent mean log reduction of triplicate samples. Prefix ‘>’ indicates no microorganisms were recovered at the assay time period, demonstrating a complete kill of the microbial challenge, for calculation these were considered to be 1 CFU, the enumeration limit of detection of the undiluted extract