Skip to main content

Table 3 OFM-Ag Antimicrobial Effectiveness Spectrum and Wear Time Data

From: Ionic silver functionalized ovine forestomach matrix – a non-cytotoxic antimicrobial biomaterial for tissue regeneration applications

Microbial Type

Species

Log Reduction Value

1 Day

3 Days

7 Days

Gram positive

Methicillin Resistant Staphylococcus aureus (MRSA)

7.0

> 8.5

7.8

Staphylococcus epidermidis (coagulase negative)

8.3

> 8.6

> 8.6

Streptococcus pyogenes (Group A, β-hemolytic)

> 7.6

> 7.6

> 7.6

Vancomycin Resistant Enterococcus faecalis (VRE)

7.5

7.8

> 8.2

Gram negative

Acinetobacter baumannii

> 8.6

> 8.6

> 8.6

Escherichia coli

> 6.9

> 6.9

> 6.9

Pseudomonas aeruginosa

> 9.6

> 9.6

> 9.6

Fungi

Candida albicans

6.1

> 8.9

> 8.9

Candida parapsilosis

7.3

> 7.6

> 7.6

Candida glabrata

6.6

> 8.5

> 8.5

Aspergillus brasiliensis (niger)

1.8

> 5.3

> 5.3

  1. Values represent mean log reduction of triplicate samples. Prefix ‘>’ indicates no microorganisms were recovered at the assay time period, demonstrating a complete kill of the microbial challenge, for calculation these were considered to be 1 CFU, the enumeration limit of detection of the undiluted extract