Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research

Biomaterials Research

Table 5 Summary of studies using glycerol-preserved (GBP) bone allograft for spine fusion

Study	Graft Type	Preservation	Patient #	Levels	3 Month Fusion	6 Month Fusion	12 Month Fusion	3 Month Avg^b Subsidence	6 Month Avg^b Subsidence
Graham [22]	Cloward Dowel	Glycerol-Preserved	53 (113 levels)	1–4	–	> 95%	–	2.09	2.12
Graham [22]	Cloward Dowel	Freeze-Dried	53 (114 levels)	1–4	–	> 95%	–	2.73	2.83
Rodway [23]	CPBA^a	Glycerol-Preserved	28 (64 Levels)	1–4	45.3% (29 Patients)	–	100%	–	–
Rodway [23]	CPBA^a	Frozen	37 (70 Levels)	1–4	41.4% (38 Patients)	–	100%	–	–

^aComposite Pinned Bone Allograft
^bCalculated by multiplying average level subsidence by number of cases for that level, then taking the sum for all levels and dividing by total number of patients

ISSN: 2055-7124