Fig. 6
From: Cosmeceutical activities of ethanol extract and its ethyl acetate fraction from coffee silverskin
The effect of the 50% EtOH extract and EtOAc fraction of coffee silverskin on melanin synthesis. Cell viability determined using the MTT assay (a), effects of the 50% EtOH extract of coffee silverskin and its EtOAc fraction and caffeine on α-MSH-induced melanin synthesis (b and c) in B16F1 melanoma cells treated with different concentrations of the extract for 72 h. Data are presented as the mean ± S.D. values. *p < 0.05 compared with the α-MSH-treated control, #p < 0.05 compared with the untreated control