Fig. 6

Dual-mode imaging guides multifunctional theranosomes (TNS): (a) Design concept of TPP/IR780/Ce6 TNS, (b) Mitochondria-targeting activity of TPP/IR780/Ce6 TNS in HeLa cells after 6 h of incubation, (c) Intracellular ROS generation of light-irradiated TPP/IR780/Ce6 TNS detected by 2′,7′-dichlorodihydrofluorescein diacetate (DCFH-DA) in HeLa cells, and (d) Tumor inhibition of laser-irradiated TPP/IR780/Ce6 TNS in HeLa tumor-bearing mice. Reproduced with permission from reference [38]; Copyright © 2018 American Chemical Society