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Table 4 Downregulated genes differentially expressed in the liver tissue of aged rats

From: Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats

  CaG5 IQG5 CS10 Description Gene Symbol
1 0.13 0.35 0.20 lysyl oxidase Lox
2 0.19 0.53 0.75 similar to Spindlin-like protein 2 (SPIN-2) LOC367746
3 0.24 0.42 0.90 serine dehydratase Sds
4 0.28 0.24 0.63 cytokine inducible SH2-containing protein Cish
5 0.29 0.64 0.65 retinol saturase (all trans retinol 13,14 reductase) Retsat
6 0.35 0.45 0.62 similar to hypothetical protein MGC42105 RGD1308116
7 0.36 0.28 0.39 solute carrier family 25, member 30 Slc25a30
8 0.36 1.01 0.39 aldo-keto reductase family 1, member B7 Akr1b7
9 0.37 0.19 0.26 one cut homeobox 1 Onecut1
10 0.38 0.66 0.68 CCR4 carbon catabolite repression 4-like (S. cerevisiae) Ccrn4l
11 0.38 0.62 1.58 patatin-like phospholipase domain containing 3 Pnpla3
12 0.38 0.49 0.95 myotubularin related protein 7 Mtmr7
13 0.39 0.18 0.26 one cut homeobox 1 Onecut1
14 0.40 0.85 1.11 keratin 10 Krt10
15 0.40 0.99 0.85 cytochrome P450, family 17, subfamily a, polypeptide 1 Cyp17a1
16 0.41 0.88 1.07 glutamate receptor, ionotrophic, AMPA 3 Gria3
17 0.41 0.70 0.65 cAMP responsive element modulator Crem
18 0.41 0.96 1.46 glycerol-3-phosphate acyltransferase, mitochondrial Gpam
19 0.42 1.00 1.49 sulfotransferase family, cytosolic, 1C, member 2 Sult1c2
20 0.42 0.30 0.44 family with sequence similarity 89, member A Fam89a
21 0.42 0.32 0.34 solute carrier family 25, member 30 Slc25a30
22 0.42 1.20 0.98 integrin, alpha 1 Itga1
23 0.45 0.73 0.80 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) Got1
24 0.45 1.29 1.05 guanine nucleotide binding protein, alpha 14 Gna14
25 0.45 0.37 0.76 similar to Urinary protein 3 precursor (RUP-3)///similar to Urinary protein 2 precursor (RUP-2) LOC68 0367///LO
26 0.46 0.81 0.74 similar to Maltase-glucoamylase, intestinal LOC679818
27 0.46 0.63 0.69 ADAM metallopeptidase domain 8 Adam8
28 0.46 0.63 0.74 G0/G1switch 2 G0s2
29 0.46 0.65 0.70 somatostatin receptor 3 Sstr3
30 0.46 0.58 0.69 cAMP responsive element modulator Crem
31 0.47 0.57 0.56 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) Rrs1
32 0.47 0.49 0.50 choline kinase alpha Chka
33 0.47 0.70 0.86 early growth response 1 Egr1
34 0.48 0.45 0.37 G patch domain containing 4 Gpatch4
35 0.48 1.15 1.11 similar to ovostatin-2 RGD1565709
36 0.48 0.42 0.66 regulator of G-protein signaling 3 Rgs3
37 0.49 0.65 0.51 tsukushin Tsku
38 0.49 0.75 1.58 mesenchyme homeobox 2 Meox2
39 0.49 0.87 0.71 cyclin D1 Ccnd1
40 0.49 0.39 1.45 phosphoglycerate dehydrogenase Phgdh
  1. PairMean ratio* means pair Mean ratio (test/control)
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