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Table 3 Upregulated genes differentially expressed in the liver tissue of aged rats

From: Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats

  CaG5 IQG5 CS10 Description Gene Symbol
1 10.69* 45.83 23.12 lipocalin 2 Lcn2
2 8.15 3.42 1.74 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Cxcl1
3 6.76 12.07 3.15 S100 calcium binding protein A8 S100a8
4 6.16 3.62 3.61 abhydrolase domain containing 3 Abhd3
5 5.21 3.56 5.38 alpha-2-macroglobulin A2m
6 4.81 3.17 5.65 myxovirus (influenza virus) resistance 2 Mx2
7 4.75 7.36 9.85 WDNM1 homolog LOC360228
8 4.45 1.79 1.22 solute carrier family 13 (sodium-dependent citrate transporter), member 5 Slc13a5
9 4.39 6.16 1.85 S100 calcium binding protein A9 S100a9
10 4.36 1.71 1.64 metallothionein 2A Mt2A
11 4.06 2.23 1.37 kininogen 1-like 1 Kng1l1
12 3.95 2.26 2.35 ATP-binding cassette, sub-family G (WHITE), member 2 Abcg2
13 3.62 1.95 1.85 protocadherin 18 Pcdh18
14 3.52 2.08 1.51 signal-regulatory protein alpha Sirpa
15 3.50 2.84 2.64 lipopolysaccharide binding protein Lbp
16 3.46 3.94 3.51 serine peptidase inhibitor, Kazal type 3 Spink3
17 3.36 4.48 2.76 CD36 molecule (thrombospondin receptor) Cd36
18 3.15 2.92 2.57 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 Serpina7
19 3.11 1.34 2.03 endothelial cell-specific molecule 1 Esm1
20 3.03 2.09 1.03 transglutaminase 1, K polypeptide Tgm1
21 2.97 1.67 0.84 basic helix-loop-helix family, member a15 Bhlha15
22 2.97 1.70 1.26 growth arrest and DNA-damage-inducible, beta Gadd45b
23 2.87 2.53 2.44 flavin containing monooxygenase 5 Fmo5
24 2.86 3.52 3.16 serine peptidase inhibitor, Kazal type 3 Spink3
25 2.86 4.39 2.74 cytochrome P450, family 7, subfamily a, polypeptide 1 Cyp7a1
26 2.85 1.75 1.47 phosphoinositide-3-kinase, class 3 Pik3c3
27 2.83 1.57 1.84 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 Slc10a2
28 2.80 1.45 1.62 neuron navigator 2 Nav2
29 2.78 2.68 1.61 stefin A2-like 3 Stfa2l3
30 2.76 1.60 1.01 STEAP family member 4 Steap4
31 2.72 1.90 1.40 desmocollin 2 Dsc2
32 2.71 1.68 1.63 lin-7 homolog a (C. elegans) Lin7a
33 2.71 2.21 2.01 tumor necrosis factor receptor superfamily, member 21 Tnfrsf21
34 2.71 1.65 1.78 metallothionein 1a Mt1a
35 2.68 1.32 1.02 interleukin 34 Il34
36 2.66 1.91 1.82 Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) Lss
37 2.66 1.60 1.24 interleukin 1 receptor, type II Il1r2
38 2.65 1.87 1.61 growth arrest specific 6 Gas6
39 2.64 4.31 1.99 interleukin 1 beta Il1b
40 2.63 2.04 1.75 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C Sema3c
  1. *Corrected for background intensity using local background correction
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