Skip to main content

Table 3 Upregulated genes differentially expressed in the liver tissue of aged rats

From: Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats

 

CaG5

IQG5

CS10

Description

Gene Symbol

1

10.69*

45.83

23.12

lipocalin 2

Lcn2

2

8.15

3.42

1.74

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Cxcl1

3

6.76

12.07

3.15

S100 calcium binding protein A8

S100a8

4

6.16

3.62

3.61

abhydrolase domain containing 3

Abhd3

5

5.21

3.56

5.38

alpha-2-macroglobulin

A2m

6

4.81

3.17

5.65

myxovirus (influenza virus) resistance 2

Mx2

7

4.75

7.36

9.85

WDNM1 homolog

LOC360228

8

4.45

1.79

1.22

solute carrier family 13 (sodium-dependent citrate transporter), member 5

Slc13a5

9

4.39

6.16

1.85

S100 calcium binding protein A9

S100a9

10

4.36

1.71

1.64

metallothionein 2A

Mt2A

11

4.06

2.23

1.37

kininogen 1-like 1

Kng1l1

12

3.95

2.26

2.35

ATP-binding cassette, sub-family G (WHITE), member 2

Abcg2

13

3.62

1.95

1.85

protocadherin 18

Pcdh18

14

3.52

2.08

1.51

signal-regulatory protein alpha

Sirpa

15

3.50

2.84

2.64

lipopolysaccharide binding protein

Lbp

16

3.46

3.94

3.51

serine peptidase inhibitor, Kazal type 3

Spink3

17

3.36

4.48

2.76

CD36 molecule (thrombospondin receptor)

Cd36

18

3.15

2.92

2.57

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

Serpina7

19

3.11

1.34

2.03

endothelial cell-specific molecule 1

Esm1

20

3.03

2.09

1.03

transglutaminase 1, K polypeptide

Tgm1

21

2.97

1.67

0.84

basic helix-loop-helix family, member a15

Bhlha15

22

2.97

1.70

1.26

growth arrest and DNA-damage-inducible, beta

Gadd45b

23

2.87

2.53

2.44

flavin containing monooxygenase 5

Fmo5

24

2.86

3.52

3.16

serine peptidase inhibitor, Kazal type 3

Spink3

25

2.86

4.39

2.74

cytochrome P450, family 7, subfamily a, polypeptide 1

Cyp7a1

26

2.85

1.75

1.47

phosphoinositide-3-kinase, class 3

Pik3c3

27

2.83

1.57

1.84

solute carrier family 10 (sodium/bile acid cotransporter family), member 2

Slc10a2

28

2.80

1.45

1.62

neuron navigator 2

Nav2

29

2.78

2.68

1.61

stefin A2-like 3

Stfa2l3

30

2.76

1.60

1.01

STEAP family member 4

Steap4

31

2.72

1.90

1.40

desmocollin 2

Dsc2

32

2.71

1.68

1.63

lin-7 homolog a (C. elegans)

Lin7a

33

2.71

2.21

2.01

tumor necrosis factor receptor superfamily, member 21

Tnfrsf21

34

2.71

1.65

1.78

metallothionein 1a

Mt1a

35

2.68

1.32

1.02

interleukin 34

Il34

36

2.66

1.91

1.82

Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

Lss

37

2.66

1.60

1.24

interleukin 1 receptor, type II

Il1r2

38

2.65

1.87

1.61

growth arrest specific 6

Gas6

39

2.64

4.31

1.99

interleukin 1 beta

Il1b

40

2.63

2.04

1.75

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Sema3c

  1. *Corrected for background intensity using local background correction