Umbilical cord mesenchymal stem cells derived extracellular vesicles can safely ameliorate the progression of chronic kidney diseases

Table 1 Entry selection criteria of the treatment group (A) patients

Patient	Age	Gender	CKD	Weight	Comorbidities	UACR	S. Creat.	Bl. Urea	e-GFR
No/G	Yrs		years	Kgm.		mg/g	mg/dl	mg/dl	ml/min.
1/A	40	M	6	77	DM, HTN	1135	3.1	122	30
2/A	26	F	8	64	DM, SLE, HTN	1527	4.3	124	32
3/A	35	F	5	62	IN, HTN	1542	3.5	125	32
4/A	44	F	7	78	IN, HTN	1375	3.6	131	37
5/A	26	M	9	63	HTN	1298	3.8	124	26
6/A	37	M	8	65	DM, HTN	1273	3.1	122	29
7/A	33	F	7	61	DM, IN	1722	4.1	143	26
8/A	34	F	12	62	IN, HTN	1372	2.4	112	31
9/A	28	F	7	69	SLE, HTN	1578	4.1	152	28
10/A	30	F	8	60	HTN	1677	3.3	127	41
11/A	29	F	9	62	SLE, HTN	1744	3.2	124	29
12/A	40	F	13	59	DM	2133	2.8	113	34
13/A	37	M	7	69	DM, HTN	1673	3.6	132	32
14/A	35	M	15	61	IN, HTN	1273	3.8	148	37
15/A	39	M	9	68	DM	1422	3.2	121	32
16/A	41	M	6	59	DM, HTN	1566	2.6	117	34
17/A	37	M	8	74	DM	1433	3.7	134	26
18/A	28	F	12	63	HTN	2133	2.9	116	29
19/A	34	F	9	68	DM, IN	1573	3.8	87	25
20/A	28	M	11	77	HTN	1677	3.8	132	25

Mean age 32.154 ± 9.21year. 50% were males. The median body weight 66.05 ± 9.31 kgm. Seventy five percent (15/20) were hypertensive, fifty percent (10/20) were T1D, twenty five percent (5/20) were interstitial nephritis and fifteen percent (3/20) were systemic lupus erythematosus. (IN, interstitial nephritis; S. creat. Serum creatinine; DM, diabetes mellitus; HTN, hypertension; eGFR, estimated glomerular filtration rate)

ISSN: 2055-7124