Table 1 Three stromal cell-seeding compositions for creating 4 distinct microenvironments in a mouse
From: Multiple genetically engineered humanized microenvironments in a single mouse
| Â | Composition A | Composition B | Composition C |
|---|---|---|---|
Implant site 1 | Growth-competent mBMSCs secreting hVEGFa | Growth-competent mBMSCs secreting hVEGFa + hBMSCs | Growth-arrested mBMSCs secreting hVEGFa |
Implant site 2 | Growth-competent mBMSCs secreting hSDF1a | Growth-competent mBMSCs secreting hSDF1a + hBMSCs | Growth-arrested mBMSCs secreting hSDF1a |
Implant site 3 | Growth-competent mBMSC ssecreting hTNFa | Growth-competent mBMSCs secreting hTNFa + hBMSCs | Growth-arrested mBMSCs secreting hTNFa |
Implant site 4 | Growth-competent mBMSCs control | Growth-competent mBMSCs control + hBMSCs | Growth-arrested mBMSC control |