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Table 2 Advantages and disadvantages of various 3D bioprinting methods for tissue engineering applications

From: 3-dimensional bioprinting for tissue engineering applications

Methods Advantages Disadvantages Materials Ref.
SLA, DLP • Manufactured simple and complex • Expensive equipment and materials PEG, PCL, PEG-co-PDP, PEGDA. [4548]
• Fast and good resolution • Only photopolymers
• No need for support materials • Cytotoxicity of uncured photoinitiator
FFF • Easy to use • Materials limited to thermoplastics PCL/PLGA/β-TCP, PCL/PLGA [50, 51]
• Good mechanical properties • Filament required
• Solvent not required • Cannot used with cells
SLS • No need for support materials • Rough surface PCL/HA, PCL, HA/PEEK, Titanium. [5962]
• Various of biomaterials • Expensive and cumberstone equipment
Inkjet • Cells and hydrogel printed • Limited biomaterials suite Collagen/PDL, Fibrin, Gelatin. [6365, 68]
• Incorporation of drug and biomolecules • Low resolution
• Low mechanical properties