Scheme 1From: Encapsulation of pancreatic islet with HMGB1 fragment for attenuating inflammationThe pancreatic islet and HMGB1 A box protein were co-encapsulated in the alginate bead. The encapsulated HMGB1 A box protein may protect islets from HMGB1-mediated inflammation via competitive inhibition against TLR and/or RAGE on immune cells. By this action, this co-encapsulation of HMGB1 A box protein could reduce early graft loss in islet transplantationBack to article page