Fig. 4From: Encapsulation of pancreatic islet with HMGB1 fragment for attenuating inflammationSecreted amount of TNF-α of activated macrophage during co-culture of alginate bead with islets and HMGB1 A box protein. HMGB1-activated macrophage Raw 264.7 cells were co-cultured with unencapsulated islets, encapsulated islets, and encapsulated islets with HMGB1 A box protein. Data were represented as means ± SEM (n = 5). *P < 0.001Back to article page