Fig. 7
From: Angiogenin-loaded fibrin/bone powder composite scaffold for vascularized bone regeneration
Goldner’s Masson trichrome staining of regenerated bone in the central area of the calvarial defect after implantation for 4 weeks and 8 weeks. After implantation for 4 weeks, mature bone (arrow) was distinctly observed around the residual material bone particles in the angiogenin-containing groups. Chronic inflammatory cells were also observed to infiltrate all defect areas. After implantation for 8 weeks, the greatest extent of regenerated bone (arrow) and blood vessels (arrowhead) was observed in the FB/ANG 2.0 group. Asterisk: residual material bone particles. Scale bar = 250 μm