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Fig. 3 | Biomaterials Research

Fig. 3

From: Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects

Fig. 3

Histologic view after 2 weeks of healing, showing – (a) control group; defect is mainly occupied by the overlying soft tissues that had collapsed into the space. (b) Collagen membrane group; membrane appeared structurally intact and displayed close marginal adaptation to the native bone at the perimeter of the defects. (c) Bone graft group; defect space is well-maintained compared to the EDC group. (d) Bone graft with collagen membrane group; defect space is well-maintained by the barrier membrane and the supporting bone graft particles. X40 magnification view, Trichrome staining

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