From: New approach for the treatment of osteoradionecrosis with pentoxifylline and tocopherol
| Score | Event | |
|---|---|---|
| NCICTC* [31] | 0 | None |
| 1 | Asymptomatic and detected by imaging only | |
| 2 | Symptomatic and interfering with function, but not interfering with activities of daily living | |
| 3 | Symptomatic and interfering with activities of daily living | |
| 4 | Symptomatic, or disabling | |
| Store & Boysen [9] | 0 | Mucosal defects only |
| 1 | Radiological evidence of necrotic bone with intact mucosa | |
| 2 | Positive radiological findings with denuded bone intra-orally | |
| 3 | Clinically exposed radionecrotic bone, verified by imaging techniques, along with skin fistulas and infection | |
| Glanzmann & Gratz [47] | 1 | Bone exposure without signs of infection and persisting for at least three months |
| 2 | Bone exposure with signs of infection or sequester and without the signs of grade 3 ± 5 | |
| 3 | Bone necrosis treated with mandibular resection with a satisfactory result | |
| 4 | Bone necrosis with persisting problems despite mandibular resection | |
| 5 | Death due to osteoradionecrosis |