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Table 5 Scoring systems of ORN

From: New approach for the treatment of osteoradionecrosis with pentoxifylline and tocopherol

  Score Event
NCICTC* [31] 0 None
1 Asymptomatic and detected by imaging only
2 Symptomatic and interfering with function, but not interfering with activities of daily living
3 Symptomatic and interfering with activities of daily living
4 Symptomatic, or disabling
Store & Boysen [9] 0 Mucosal defects only
1 Radiological evidence of necrotic bone with intact mucosa
2 Positive radiological findings with denuded bone intra-orally
3 Clinically exposed radionecrotic bone, verified by imaging techniques, along with skin fistulas and infection
Glanzmann & Gratz [47] 1 Bone exposure without signs of infection and persisting for at least three months
2 Bone exposure with signs of infection or sequester and without the signs of grade 3 ± 5
3 Bone necrosis treated with mandibular resection with a satisfactory result
4 Bone necrosis with persisting problems despite mandibular resection
5 Death due to osteoradionecrosis
  1. *NCICTC: Common Toxicity Criteria of the National Cancer Institute.