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Table 3 Classification of ORN by Epstein et al. [[7]

From: New approach for the treatment of osteoradionecrosis with pentoxifylline and tocopherol

Stage

Description

Symtoms

Treatment

I

Resolved, healed

None

Follow-up, prevention of recurrence

Ia

No pathologic fracture

  

Ib

Pathologic fracture

 

Reconstructed

II

Chronic, persistent non-progressive

None, or controlled

Local wound care

Antiseptics/antibiotics, analgesics, hyperbaric oxygen (if indicated)

IIa

No pathologic fracture

  

IIb

Pathologic fracture

Jaw dysfunction

 

III

Active, preogressive

Progressive

Local wound care

Antiseptics/antibiotics, analgesics, hyperbaric oxygen (if indicated)

IIIa

No pathologic fracture

  

IIIb

Pathologic fracture

Jaw dysfunction

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