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Fig. 8 | Biomaterials Research

Fig. 8

From: Psoralen synergies with zinc implants to promote bone repair by regulating ZIP4 in rats with bone defect

Fig. 8

The promotional mechanism of Zn + CS/pPRL implants on bone formation in rats with bone defects. (A) Representative image of FluoZin-3-stained femur with bone defects. (B)The fluorescence quantification analysis of Zn2+ concentrations. (C) The serum concentrations of Zn2+ detected using ICP. (D) The expression of ZIP4 mRNA in femur with bone defects was detected using RT-qPCR (n = 3). (E) The expression of Runx2, Alpl, Osterix mRNA in femur with bone defects were detected by RT-qPCR (n = 3). Bars represent mean ± S.D. *p < 0.05; **p < 0.01

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