Fig. 8
From: Self-assembling biomolecules for biosensor applications
a Components of an impedimetric biosensor and the equivalent electric circuits (EEC) and Nyquist diagram for interpreting electrochemical impedance spectroscopy (EIS) data. b Electrochemical identification of BCSCs on electrodes using multifunctional nanofibers and data plot of results showing detection of BCSCs targeted by a surface-functionalized electrode. Curve a indicates the presence of BCSCs. Reprinted with permission from ref. [117]; Copyright 2019, American Chemical Society. c Silicon micropillar arrays functionalized with self-assembling peptides to form comprehensive circuits in blood vessels and the circuit diagram of a 3D biosensor for impedimetric sensing. (Re: Electrode resistance, Rs: Solution resistance, Rsi: Substrate resistance, Rct: Charge transfer resistance, Cdl: Double layer capacitance, CCTX − B: Capacitance of CTX-B). Reprinted with permission from ref. [118]; Copyright 2019, American Chemical Society. d Schematic image of the 3D sensor constructed with working and reference SiMP pairs (Pristine & Peptide) in the blood plasma system [119]