Scheme 1
From: A polymeric nanocarrier that eradicates breast cancer stem cells and delivers chemotherapeutic drugs
HA-b-PCDA as a nanocarrier to deliver drugs and eradicate BCSCs. A HA-b-PCDA can intact with 35 common clinical chemotherapeutic drugs to form stable complexes verifying by the molecular docking and molecular dynamics study, and represented drug-loaded HA-b-PCDA nanoparticles were prepared and characterized. B HA-b-PCDA could activate the Hippo pathway and inhibit the JAK2/STAT3 pathway to eradicate BCSCs