Fig. 2

a H&E staining of main organs (heart, liver, spleen, lung, and kidney) and GI tract (stomach, small intestine, and colon) after intravenous administration of 200 μL NS or 0.2 M concentrations of Ho-DOTA after different time points (1 and 14 days); b Body weight fluctuations in mice injected with Ho-DOTA (n = 3) or treated with NS (n = 3) for 1d and 14 days; c Data was expressed as mean ± standard deviation. Typical biomarkers of liver and kidney function in mice injected with Ho-DOTA, iohexol and NS respectively (n = 3) for 1 day and 14 days. Data was expressed as mean ± standard deviation