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Table 1 Applications of CINMs-based PTT in cancer therapy and imaging

From: Photothermal therapy of copper incorporated nanomaterials for biomedicine

Nanomaterial

Therapeutic remarks

Laser parameters

Tumor model

Reference

IPNs

PTT/chemotherapy/PDT

980 nm, 2.0 W·cm−2, 15 min

4T1 tumor

[14]

Cu2O@CaCO3@HA (CCH)

PTT/PDT/CDT/immunotherapy

1064 nm, 0.5 W·cm−2, 5 min

CT26.WT tumor

[15]

LDH-CuS

PTT/CDT/PDT/PAI/lysosome-targeting

808 nm, 1.5 W·cm−2, 5 min

4T1 tumor

[39]

Gox@CuS

PTT/CDT/PDT/starvation therapy

808 nm, 5.0 W·cm−2, 10 min

B16F10 tumor

[40]

TRF-mCuGd

PTT/CDT/MRI

808 nm, 0.8 W·cm−2, 10 min

MDA-MB-231 and MCF-7/DDP tumors

[27]

Cu3BiS3 nanorods

PTT/radiotherapy/PAI/CT

1064 nm, 1.0 W·cm−2, 6 min

4T1 tumor

[41]

Cu2MoS4 (CMS)/Au

PTT/PDT/immunotherapy/CT/PAI

808 nm, 0.5 W·cm−2, 5 min

U14 tumor

[19]

BCGCR

PTT/CDT/MRI/NIRF

980 nm, 0.8 W·cm−2, 10 min

U87MG tumor

[42]

HMSNs@PDA-Cu

PTT/CDT

808 nm, 0.6 W·cm−2, 3 min

MCF-7 tumor

[43]

ICG/Cu-LDH@BSA-DOX

PTT/PDT/chemotherapy

808 nm, 0.3 W·cm−2, 2 min

B16F0 tumor

[44]

HMON@CuS/Gd

PTT/PDT/MRI/fluorescence

808 nm, 0.8 W·cm−2, 8 min

HGC-27 tumor

[45]

CuS NPs-PEG-Mal

PTT/immunotherapy

808 nm, 0.45 W·cm−2, 5 min

4T1 tumor

[46]

FA-CD@PP-CpG

PTT/PDT/chemotherapy/immunotherapy

650 nm, 4.5 mW·cm−2, 5 min for PDT; 808 nm, 0.987 W·cm−2, 5 min for PTT

4T1 tumor

[47]

CuS@OVA-PLGA-NPs

PTT/immunotherapy

980 nm, 1.0 W·cm−2, 10 min

4T1 tumor

[48]

CuS-SF@CMV

PTT/immunotherapy/chemotherapy

808 nm, 0.6 W·cm−2, 5 min

H22 tumor

[49]

Cu2MnS2 NPs

PTT/MRI/MSOT

1064 nm, 0.6 W·cm−2, 10 min

S180 tumor

[50]

Cu2ZnSnS4 (CZTS)@BSA

PTT/MRI/PAI

808 nm, 1.0 W·cm−2, 5 min

H22 tumor

[51]

Cu2-xSe-Au Janus NPs

PTT/CDT/photocatalytic therapy/CT/PAI

808 nm, 0.36 W·cm−2, 10 min

4T1 tumor

[52]

C-m-ABs

PTT/PDT/CDT/chemotherapy/MRI/PA/NIRF

808 nm, 1.4 W·cm−2, 8 min

MGC-803 tumor

[53]

Au@Cu2O

PTT/PAI

808 nm, 1.0 W·cm−2, 5 min

HCT tumor

[22]

Core–satellite nanoconstructs (CSNC)

PTT/PDT/PET/fluorescence/Cerenkov luminescence/Cerenkov radiation energy transfer

980 nm, 4.0 W·cm−2, 10 min for PTT; 660 nm, 0.05 W·cm−2, 20 min for PDT

4T1 tumor

[54]

BPMN-CuS/DOX

PTT/chemotherapy/CDT

808 nm, 1.0 W·cm−2, 3 min

B16F10 tumor

[55]

PZTC/SS/HA

PTT/CDT

1064 nm, 1.0 W·cm−2, 10 min

HCT-116 tumor

[56]

Cu-BTC@PDA

PTT/CDT

808 nm, 1.0 W·cm−2, 10 min

B16F10 tumor

[57]

CAL@PG NPs

PTT/chemotherapy/CDT

1064 nm, 1.35 W·cm−2, 10 min

MHCC97H tumor

[58]

Cu(II)/LRu/PDA NPs

PTT/PDT/MRI/photoacoustic tomography

808 nm, 1.0 W·cm−2, 12 min for PTT; 660 nm, 1.0 W·cm−2, 12 min for PDT

HeLa tumor

[59]