Fig. 8

CINMs for MRI- and CT-guided PTT. A Synthetic procedures of PFN. B Longitudinal relaxation rate (r₁) of PFN. C T₁WI and (D) signal intensities of tumor-bearing mice at various time intervals after PFN treatment. Reproduced with permission [177]. Copyright 2020, American Chemical Society. Linear fits of 1/T₁ for CuS HNs, Magnevist (T₁WI contrast agent) and Fe₃O₄ (T₂WI contrast agent) at different (E) molar concentrations of Cu, Gd and Fe and (F) mass concentrations. G In vitro MRIs of different mass concentrations of CuS + DOX aqueous dispersions, and MRI of tumor-bearing mice treated with CuS + DOX (1.0 mg mL⁻¹, 100 μL). Reproduced with permission [90]. Copyright 2018, Royal Society of Chemistry. H In vitro CT images of different concentrations of Cu₃BiS₃ NCs aqueous dispersions. I CT value as a function of Cu₃BiS₃ NCs concentration. J CT coronal images of tumor-bearing mice after intratumoral injection and intravenous injection of Cu₃BiS₃ NCs. Reproduced with permission [77]. Copyright 2015, Wiley-VCH. (K) Linear fit of HU values of T80-AuPt@CuS NSs and iohexol solution at different concentrations. L CT images of tumor-bearing mice treated with T80-AuPt@CuS NSs. Reproduced with permission [156]. Copyright 2021, American Chemical Society