Fig. 6
From: Photothermal therapy of copper incorporated nanomaterials for biomedicine
CINMs-based PTT/radiotherapy combination therapy. A Synthetic procedures and therapeutic mechanisms of CuxS/Au-PEG NPs. B Thermal images and C photothermal conversion abilities of CuxS/Au-PEG NPs under 1064 nm laser irradiation in tumor-bearing mice. D Immunofluorescence images and (E) quantification of tumor hypoxic regions after NIR irradiation (***p < 0.001). Reproduced with permission [158]. Copyright 2020, American Chemical Society. F Transmission electron microscopy (TEM) image and (G) high-angle annular dark-field-scanning TEM energy dispersive spectrometer elemental mapping image of CSA NPs. H Live-dead staining of 4T1 cells treated with different power densities of NIR light and different CSA NPs concentrations. I Cell survival rates and (J) DNA damage images of 4T1 cells after different treatments. K Isobologram analysis of synergistic inhibition of 4T1 cells treated with CSA NPs by applying laser and X-rays. Reproduced with permission [73]. Copyright 2019, American Chemical Society. L Schematic presentation of the scheme for radiolabeling and purification of Fe3O4@Au@Cu2-xS using 64Cu. M In vitro stability of 64Cu: Fe3O4@Au@Cu2-xS in PBS and human serum at 37 °C. Reproduced with permission [159]. Copyright 2022, Wiley-VCH