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Fig. 5 | Biomaterials Research

Fig. 5

From: Polymer composite microspheres loading 177Lu radionuclide for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer

Fig. 5

Evaluation of the in vivo anti-tumor efficacy of 177Lu-PDA-CS-MgO microspheres. A. Representative MRI monitoring of rat livers in 5 w post radioembolization. Yellow circles point out the primary focus and arrows point out new tumor lesions during treatment. B. Tumor volume in each group at 0 w, 1 w, 3 w and 5 w. C. Tumor numbers in each group at 0 w and 5 w. D. Survival curves of rats in each group. E. Representative immunohistochemical staining and semi-quantitative analysis of H&E, TUNEL, Ki-67, CD-31 and HIF-1α in tissue samples post-treatment. The scale bar is 100 μm. F. Western Blot analysis of typical biomarkers, including HIF-1α, VEGFRα, Bax and Bcl-2 in liver tissues

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Biomaterials Research

ISSN: 2055-7124

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