Fig. 6
From: Application of advanced biomaterials in photothermal therapy for malignant bone tumors
Schematic illustration of the fabrication and application of the UCNP-Au-Alg hydrogel in the PTT of tumor and bone rehabilitation. A Injection of UCNP-Au-Alg into the high Ca2+ environment of bone tissue accelerated its mechanically stable formation of it. B X-ray images from different periods of PBS and UCNP-Au-Alg hydrogel treatment of the tibia, where the red dotted circles represent the distinction between defects. Scale bar: 1 cm. C 3D micro-CT images of the tibias treated by PBS or UCNP-Au-Alg hydrogel 14 days after treatment. Scale bar: 1 mm. D Pathological sections of tibias treated by PBS and UCNP-Au-Alg hydrogel 14 days after surgery. Abbreviation: NaGdF4:Yb, Er@NaGdF4:Yb, Nd (UCNP), polyethyleneimine (PEI), alginate (Alg). Reproduced with permission from Ref. [151]