Fig. 8

Total RNA sequencing analysis. a Scatter plot. The red and blue dots indicate up-regulated and down-regulated genes, respectively, of the 44ºC heat treated-MSCs compared to the control. b Volcano plot. c Ten major gene ontologies closely related with the genes, which showed significantly altered expressions induced by HT. d Heat map of the two repeated analysis for each gene which are involved in the listed gene ontologies. e Specific gene expression profiles of each gene ontology; apoptosis, aging, and cell cycle