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Fig. 3 | Biomaterials Research

Fig. 3

From: Metal-organic framework-based photodynamic combined immunotherapy against the distant development of triple-negative breast cancer

Fig. 3

In vitro antitumor effects of nanocomplexes. a The cell cytotoxicity of BMS-202, PCN-224/HP and BMS@P/HP NPs for the normal cell L929 by MTT assay. b The cell cytotoxicity of BMS-202, PCN-224/HP and BMS@P/HP NPs for the tumor cell 4T1 by MTT assay. (n = 3, *P < 0.05, **P < 0.01, ***P < 0.001, ***P < 0.001, ****P < 0.0001). c After treatment with different drugs, 4T1 cells were tested for LIVE/DEAD. Living and dead cells were stained with Calcein-AM (green) and PI (red), respectively. Scale bar: 100 μm. d Flow cytometry and (e) fluorescence microscopy were used to detect ROS levels in 4T1 cells. Scale bar: 100 μm

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