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Fig. 6 | Biomaterials Research

Fig. 6

From: Mesenchymal stem cell-derived secretomes-enriched alginate/ extracellular matrix hydrogel patch accelerates skin wound healing

Fig. 6

In-depth analysis of the wound tissues via immunofluorescence staining. (A) Representative immunofluorescence images of wound tissues on day 7 (green: cytokine10 (K10), blue: DAPI). The yellow arrow indicates the wound edges. Scale bar is 500 μm. (B) Representative images of mature neovessels as assessed via co-immunofluorescence of α-SMA (green) and CD31 (red), along with DAPI staining. The yellow triangles denote mature vessels. Scale bar is 50 μm. (D) Quantitative analysis of the epidermis area (%), which was K10 negative on day 7. (E) Quantitative measurement of average mature vessel size on day 14. Statistically significant difference (***p < 0.001, ****p < 0.0001)

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