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Fig. 5 | Biomaterials Research

Fig. 5

From: Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans

Fig. 5

A MTT activity and B ATP content of C. albicans (a) before being cultured, (b) after being cultured with S. boulardii bioactive material, and (c) after being cultured with S. boulardii (pGK1-Mcp1) bioactive material for 2 h. C Fluorescent images and schematic diagram of mitochondrial membrane potential (Ψm) of C. albicans before and after being cultured with S. boulardii bioactive material and then stained by JC-1. (a), (b), and (c) are the same as in (A). Bar = 50 μm. D ROS, E SOD1, F CAT, and G GSH of C. albicans before and after antagonism. (a) Control, (b) culturing with S. boulardii bioactive material, and (c) culturing with S. boulardii (pGK1-MCP1) bioactive material. H Schematic diagram of antagonistic mechanism of S. boulardii (pGK1-MCP1) bioactive material against C. albicans. Statistical significance was defined based on the different p-values: *p < 0.05, **p < 0.01, and ***p < 0.001

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Biomaterials Research

ISSN: 2055-7124

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