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Fig. 4 | Biomaterials Research

Fig. 4

From: Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans

Fig. 4

A Schematic diagram of GFP-labeled C. albicans. B Fluorescence images of GFP-labeled C. albicans. The C. albicans (Csp37-GFP) was cultured in YPD medium and RPMI-1640 medium for 4 h and then observed by fluorescence microscope. Bar = 50 μm. C ImageJ analysis of GFP-labeled C. albicans after being cultured in YPD medium and RPMI-1640 medium. D Antagonism of tube coating (S. boulardii bioactive material) against C. albicans adhesion. The tube coatings of GelMA hydrogel, S. boulardii bioactive material, and S. boulardii (pGK1-Mcp1) bioactive material were cultured with C. albicans (Csp37-GFP) for 2 h and then detected by fluorescence microscope. Bar = 50 μm. E ATP contents and F MTT test results of S. boulardii and S. boulardii (pGK1-Mcp1) in bioactive material after culturing with C. albicans for 2 h. G Mitochondrial respiratory chain complex III of S. boulardii and S. boulardii (pGK1-MCP1) in bioactive material after culturing with C. albicans for 2 h. Statistical significance was defined based on the different p-values: *p < 0.05, **p < 0.01, and ***p < 0.001

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Biomaterials Research

ISSN: 2055-7124

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