Fig. 7From: Time-sequential fibroblast-to-myofibroblast transition in elastin-variable 3D hydrogel environments by collagen networksModel of the FMT on elastin-variable 3D hydrogel environments. Among the four types of elastin-variable hydrogels (100C, 4C1E, 1C1E, and 1C4E), 20% elastin in 4C1E induces the FMT via calcium signaling. The FMT is demonstrated by an increase in collagen synthesis and increased expression of biomarkers (S100A4, PDFGR-β, THY-1, FHL1, FBN1, and α-SMA). Back to article page