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Table 3 Drug content in brain tissues and brain homogenate obtained by liquid–liquid extraction and subsequently analyzed using LC/MS/MS

From: Controlled release of Clenbuterol from a hydroxyapatite carrier for the treatment of Alzheimer’s Disease

 

Concentration (ng/mL)

24 h after injection

Concentration (ng/mL)

56 days after AD treatment

CLB

5.24 ± 1.81

 N.A.

SHAP-CLB

16.08 ± 2.66

2.38 ± 0.31