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Fig. 8 | Biomaterials Research

Fig. 8

From: GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor model

Fig. 8

In vivo evaluation of long-term immunological memory by tumor rechallenge. A Schematic diagram of experimental design. B Weight fluctuations during treatment (n = 3). C Tumor volume of second tumors (n = 3). (D) Survival curves of mice (n = 6). Levels of pro-inflammatory cytokines including IFN-γ (E), IL-6 (F) and TNF-α (G). (*P < 0.05, ****P < 0.0001). a: Control, b: Bif@PAu-NPs, c: Bif@PAu-NPs + NIR, d: Bif@PAu-NPs + NIR + GM-CSF.

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