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Fig. 5 | Biomaterials Research

Fig. 5

From: GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor model

Fig. 5

In vivo evaluation of antitumor efficacy. A Schematic diagram of the treatment procedure. B Representative photographs of CT-26 tumor-bearing mice on day 14 of post-treatment (n = 3). C Representative photographs of isolated tumors (n = 3). D Tumor weights. E Tumor volume (n = 6). F Change of body weight (n = 6). G Survival curves of mice (n = 6). H Immunofluorescence images of CD4, CD8, CRT and HMGB1, HE staining of tumors. scale bar = 50 μm. (*P < 0.05, ****P < 0.0001). I: Control; II: Bif + NIR + GM-CSF; III: PAu-NPs + NIR + GM-CSF; IV: Bif@PAu-NPs + GM-CSF; V: Bif@PAu-NPs + NIR; VI: Bif@PAu-NPs + NIR + GM-CSF

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