Fig. 4From: GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor modelTargeting ability of Bif@PAu-NPs hybrids. A Representative photographs of bacterial growth in heart, liver, spleen, lung, kidney and tumor tissues on days 1, 4, 7 and 14 after Bif@PAu-NPs injection in CT-26 tumor-bearing mice. B Number of Bif@PAu-NPs colonization in liver, kidney and tumor. C Schematic diagram of in vitro hypoxia model using Transwell Chambers. D Bacteria number in Transwell chambers. E Fluorescence images of tumors. (Red: hypoxic zone, green: Bif, scale bar = 20 μm). F Fluorescence intensity of Bif@PAu-NPs and hypoxic zone along the yellow line). (***P < 0.001, ****P < 0.0001)Back to article page