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Fig. 3 | Biomaterials Research

Fig. 3

From: GM-CSF augmented the photothermal immunotherapeutic outcome of self-driving gold nanoparticles against a mouse CT-26 colon tumor model

Fig. 3

In vitro cellular experiments. Cellular uptake of in vitro photothermal therapy (A) Cell uptake of NR-labeled nanoparticles (scale bar 50 μm). B Schematic diagram of in vitro PTT. C Cell viability of CT-26 cells. (n = 3). D cell viability of AML-12 cells incubated with Bif@PAu-NPs for 24 h (n = 3). E Cell viability of CT-26 cells with different treatments. F Live/dead staining of CT-26 cells with Calcein AM (green, live cells), PI (red, dead cells). The white dashed line represents the boundary line of laser irradiation. Scale bar = 500 μm. G Apoptosis rate of each group. I: Control; II: Au-NPs; III: PAu-NPs; IV: Bif@PAu-NPs; V: NIR; VI: Au-NPs + NIR; VII: PAu-NPs + NIR; VIII: Bif@PAu-NPs + NIR. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Biomaterials Research

ISSN: 2055-7124

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