Fig. 9
From: mRNA nanodelivery systems: targeting strategies and administration routes
A 306-N16B (N-series) LNPs with an amide bond specifically delivered mRNA to lung via intravenous injection with high accuracy and pulmonary endothelium was mainly transfected. Reproduced with permission [143]. Copyright 2022, The Proceedings of the National Academy of Sciences. B A high proportion of PEG can promote the delivery of mRNA-LNPs to lung (group E) via nebulization. Reproduced with permission [13]. Copyright 2021, Springer Nature