Fig. 10
From: mRNA nanodelivery systems: targeting strategies and administration routes
A Schematic illustration of unique characteristics of five-element nanoparticles (FNPs) for Lung-specific mRNA delivery. Reproduced with permission [150]. Copyright 2022, American Chemical Society. B Schematic illustration of the ionizable polyester nanoparticles (polyMDET or polyMDET-Cp) for lung-selective nucleic acid transfection. Reproduced with permission [168]. Copyright 2022, American Chemical Society. C Stimulus-responsive bifunctional peptide hybrid NPs (mMMP13@RP/P-KGF) used for the treatment of idiopathic pulmonary fibrosis, and illustration and TEM images of its MMP2-responsive and pH-sensitive abilities. Reproduced with permission [174]. Copyright 2022, John Wiley and Sons