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Fig. 6 | Biomaterials Research

Fig. 6

From: GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances

Fig. 6

GelMA/CGMA hybrid hydrogels incorporated with DFO/Eth that couple angiogenesis and osteogenesis for vascularized bone regeneration. a Graphic description of the 3D bioprinting and experimental procedures of the Eth-DFO @GelMA/GGMA hydrogel scaffold. b The suitability and 3D bioprinting process of the hydrogel scaffold. c In vitro angiogenic abilities of HUVECs with different hydrogel scaffolds. d In vitro osteogenic abilities of different hydrogel scaffolds. e Vascularized bone formation induced by the Eth-DFO@GelMA/GGMA hydrogel scaffold in a rat skull defect model at 8 and 12 weeks after surgery. Images reproduced from [29], © 2022 Elsevier Ltd

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