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Fig. 7 | Biomaterials Research

Fig. 7

From: Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis

Fig. 7

In vivo inhibition of M1 macrophages activation induced by PEG-CNPs. Pro-inflammatory cytokines a IL-1β and b TNF-α levels and anti-inflammatory cytokines c IL-10 and d TGF-β1 levels with PEG-CNPs treatment in the colon tissues (n = 10). Pro-inflammatory cytokines e IL-1β and f TNF-α levels with PEG-CNPs treatment in the blood serum (n = 10). g Immunohistochemical analysis of CD86 of colon tissues from healthy or TNBS-colitis mice (n = 3). h Statistical analysis of CD86 in immunohistochemical staining (n = 3). The SOD activity i and the MDA level j with PEG-CNPs (n = 10). Data represent means ± s.d. ###P < 0.001 vs. control group; **P < 0.01, ***P < 0.001 vs. TNBS group

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Biomaterials Research

ISSN: 2055-7124

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