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Fig. 6 | Biomaterials Research

Fig. 6

From: Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis

Fig. 6

In vivo restoration of colonic epithelium by PEG-CNPs. a CLSM images to track the intracellular fate of FITC-PEG-CNPs after injection (Scale bars: 100 μm). b Immunohistochemical analysis of HIF-1α of colon tissues from healthy or TNBS-colitis mice. c Intestinal barrier functions were measured the FITC-dextran signal in blood. d Immunohistochemical analysis of occludin-1 and ZO-1 of colon tissues from healthy or TNBS-colitis mice. Statistical analysis of occludin-1 e and ZO-1 f in immunohistochemical staining. Data represent means ± s.d. n = 3. ##P < 0.01, ###P < 0.001 vs. control group; **P < 0.01, ***P < 0.001 vs. TNBS group

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