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Fig. 2 | Biomaterials Research

Fig. 2

From: Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitis

Fig. 2

PEG-CNPs ameliorate the TNBS-induced colitis in mice. a Experimental scheme of PEG-CNPs treating strategy in mice. The mice were treated with normal saline (intravenous injection) or PEG-CNPs (intravenous injection, 1.5 mg/kg) at 2 h after the TNBS administration and mice were sacrificed at day 5. b The body weights in each group for 5 d. c The DAI scores in each group for 5 d. d-h On day 5, animals were euthanized and colon images d, colon length e, and colonic MPO activity f were measured. g Representative histopathology changes in the colon. h The histopathology scores in the colon (n = 3). Data represent means ± s.d. n = 10. ###P < 0.001 vs. control group; **P < 0.01, ***P < 0.001 vs. TNBS group

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Biomaterials Research

ISSN: 2055-7124

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