Fig. 3
From: Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection
Mice vaccinated with the MΦ-NT nanovaccine can obtain rapid and long-lasting immunity. A Illustration diagram of an immunocompromised mouse vaccinated with MΦ-NT that can obviously combat bacterial infections. B Serum anti-P. aeruginosa IgG at day 7 and after vaccination with different doses of MΦ-NT and C over 16 days after treatment with different concentrations of MΦ-NT on days 0, 7, and 14. D Bacterial load in mice intratracheally challenged with 107 or 106 CFU P. aeruginosa. E DCs and F neutrophils per lung 1 day after the mice were infected with 107 CFU P. aeruginosa. G DCs and H neutrophils per 1 mL of blood 1 day after the mice were infected with 106 CFU P. aeruginosa [10]. Copyright © 2022 Zhou et al., American Association for the Advancement of Science