Table 4 List of Clinically approved polycyanoacrylate adhesives (modified from ref. [22])

B. Braun Medical Inc

(USA)

Histoacryl, Histoacryl Blue and

Hisoacryl Flexible

Cyanoacrylate derivatives

Closure of topical skin incisions and microbial barrier

[99]

Ethicon, J & J

(USA)

IFAbond

2-Octyl cyanoacrylate

Topical application on skin edges and trauma-induced lacerations

[99]

Covidien LP

(UK)

Indermil

η-Butyl cyanoacrylate

Closure of topical skin incisions

in low-skin tension

[99]

Cordis Neurovascular Inc

(USA)

Trufill

η-Butyl cyanoacrylate and ethiodized oil

Embolization of cerebral

arteriovenous malformations

[100]

Ethicon

(USA)

Omnes

2-Octyl cyanoacrylate

and butyl lactoylcyanoacrylate

Vascular reconstructions

[101]

Matrix (Italy)

Glubran2

η-Butyl cyanoacrylate

Surgeries for laparoscopic

[102]

and methacryloxysulfone

incisions and digestive tract endoscopy

Chemence Medical

(USA)

Derma + Flex

2-Octyl cyanoacrylate

and η-butyl cyanoacrylate

Topical application in skin edges

and trauma-induced lacerations

[103]

LiquiBand Technology

(UK)

LiquiBand Exceed

2-Octyl cyanoacrylate

Closure of topical skin incisions

and trauma-induced lacerations

[103]

Adhezion Biomedocal LLC (USA)

SurgiSeal

2-Octyl cyanoacrylate

Closure of topical skin incisions

and trauma-induced lacerations

[104]