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Table 1 List of clinically approved fibrin adhesives (modified from ref. [22])

From: Progress of tissue adhesives based on proteins and synthetic polymers

Company name

(country name)

Trade name

Components

Clinic applications

Ref

Baxter(USA)

Tisseel

Human fibrinogen, thrombin, fibronection bovine aprotinin

Hemostasis in surgery

[26]

Baxter(USA)

Artiss

Gelatin granules and human thrombin

Hemostasis

[27]

Ethicon, J & J(USA)

Evarrest

Human fibrinogen, thrombin

Hemostasis

[27]

Ethicon, J & J(USA)

VISTASEAL

Human fibrinogen, thrombin

Hemostasis in surgery

[28]

Haemacure(Canada)

Hemaseel

Human fibrinogen, thrombin, bovine thrombin

Hemostasis

[27]

Ethicon, J & J(USA)

Evicel

Human fibrinogen, thrombin, fibronectin

Hemostasis on the liver surface

[27]

Stryker(USA)

Vitagel

Bovine collagen, bovine thrombin, patient's own plasma

Hemostasis in surgery procedure

[29]

Baxter(USA)

Tachosil

Equine collagen patch, human fibrinogen, human thrombin

Hemostasis in cardiovascular and hepatic forgery

[30]

LFB-Lille(France)

Biocol

Human fibrinogen, thrombin, polyphosphate, calcuim

Hemostasis (Commercially approved TA-2)

[31]

KM Biologics Co., Ltd. (Japan)

Bolheal

Human fibrinogen, thrombin, coagulation factor XIII, calcium

Hemostasis

[31]

Aventis Behring

(Germany)

Beriplast P

Human fibrinogen, thrombin, coagulation factor XIII, calcium

Hemostasis

[31]