Fig. 6
From: Progress of tissue adhesives based on proteins and synthetic polymers
Synthesis, application, and in vitro characterization of GelCORE adhesive hydrogels: A Schematic of the chemical reaction for GelCORE formation and photocrosslinking of the prepolymer solution with Eosin Y (photoinitiator), TEA (co-initiator), and VC (co-monomer); B Schematic of the application of GelCORE for rapid and long-term repair of corneal injuries, which include: (i) formation of stromal defect, (ii) application of the bioadhesive, (iii) regeneration of the epithelial layer, and (iv) stromal regeneration. C Injecting the prepolymer solution into the corneal defect and exposing it to the visible light, which forms: D an adhesive GelCORE hydrogel. (Adapted from Sani et al. Science Advances 2019;5:eaav1281 with permission from AAAS [71])