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Fig. 4 | Biomaterials Research

Fig. 4

From: Self-assembled peptide-substance P hydrogels alleviate inflammation and ameliorate the cartilage regeneration in knee osteoarthritis

Fig. 4

(A) MMP-9 and type II collagen were detected by immunofluorescence staining. (DAPI: blue, MMP-9: green, type II collagen: red) Scale bars: 200 μm. (B) Apoptotic cells (green) in the articular cartilage regions were detected by TUNEL staining 6 months after surgical induction of OA. Scale bars: 50 μm. (C) The ratio of TUNEL-positive nuclei to total nuclei was quantified for each group (expressed as %, n = 3 in each group) (*, p < 0.05). (D-E) MSC recruitment by SAP-SP conjugates was investigated. Representative images of articular cartilage defect sites from each group after CD44 (green) and CD90 (red) staining. Scale bars: 100 μm

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Biomaterials Research

ISSN: 2055-7124

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